Big surprise - the 50-300 zoom looks MUCH better than the 50/1.4 at 50 mm. I'm talking about the colors, they are just better and more natural (less aberrations probably). Of course, if you have enough light since it's slower.
I investigated this, and it turns out modern lenses have much better coatings and other optimizations.
Conclusion: lens age matters too, if it's an old design investigate.