Excited about this news, this the kind of change the modern web needs.
not trying to be snarky but do you mean a desktop app?
Or maybe you could use a sqlite replication tool in the browser for near realtime changes in the master node db.
And for single user apps developped with tools like Electron having your db engine in the browser makes the app faster and life easier for the dev.
Node as app server and db backend for a single user app is inefficient, slow and resource hogging.
Using Sqlite you could get rid of node and therefore, reduce memory usage, speed up app loading and execution, have a single code base in the browser that makes debugging far easier, reduce code complexity and app size, reduce cpu cycles, energy usage and CO2 emissions, save precious life time, etc... :-)