I think it's more that HN is warping reality on how ready they are for real work. We are shaping what is going to happen next in tech, and how quickly, by being eager and ready to give things a try and, in a mix of above average skill and curiosity, being able to make it work at a fairly sophisticated level, despite its current shortcomings.
Npm packages already do too much, with package.json being used to run scripts that have permission to do nefarious tasks to relying on C libraries.
If I were to use Deno it would be with the understanding that I'd need to find dependencies that are generic and standard... Not expect everything from npm to work by default.
If I used either I'd specifically look for dependencies that are standard enough to not matter or