There are 52 weeks in 1 year. Give yourself 2 weeks vacation that leaves 50 weeks. At 40 hours per week that is 2000 hours as a full time equivalent (a salaried position). If you bill at 100/hour that is 200k/year.
If you want/need 4 weeks off, assume 1920 hours per year and adjust your hourly rate, call it ~105/hour
If your medical insurance costs 6k per year, adjust your hourly rate, call it ~107.3/hour
If you want disability/life insurance and the cost to you is 15k per year, adjust your hourly rate, call it now ~115/hour.
Giving up 50k in stock options, well that's a one time thing. Also if a relocation is required and your partner looses their positon better factor that into your decision - up front.
This all gets negotiated up front - not 4 months in.
Good luck on your next negotiation.