I currently work at a startup that uses Python for everything. Since we're data science oriented (and Python is the only programming language the data scientists kinda-sorta know). And the CTO fears having to hire for more than one backend language (even though we have more people with prior Java experience than Python, and all of the backend API developers hate working with Python).
We get by, but it's pretty awful. People will give you all sorts of arguments for why loose typing and an NPM-like sloppy ecosystem are advantages for Python. And for the domains where Python really shines (i.e. devops, and manual data-wrangling), maybe these are advantageous. But what they DON'T tell you is that best practices for large-scale backend development call for bolting-on so many extra things, and accepting so many constraints, that it wipes out the purported advantages.
You'll need to use at least one linter, if not two, and a style checker to enforce the use of type hints. This gets you to something that is maybe 50-75% as effective as a Java compiler, but will never be any better than that, and will never have anywhere near the same level of IDE integration.
If you have a lot of dependencies (and you will), then you'll need a proper build system like Poetry. Which puts you right back in that Maven world, that escaping from was supposed to be one of the advantages. And the dependency ecosystem is SO... FREAKING... BAD. Unlike Java, where most of the major libraries are professional in nature with corporate financial backing, most Python libraries are "pure" community and written by unpaid volunteers or hobbyists. Many of whom have NO understanding of semantic versioning, so you find yourself having to pin ALL of your dependencies to specific fixed versions so the spider web doesn't tangle up. Upgrading anything is a nightmare.
You'll be told that it's easier to hire for. But then you'll find that the candidate pool is largely ops or QA/QE people looking to transition into engineering, boot camp grads, and other people with no professional experience in backend API development or even Python itself. Most capable candidates that you hire will take the job for other reasons (e.g. wanting some exposure to data science or ML), and will complain constantly about having to work with Python for general backend services.
You can get by, but as the project or company grows, you'll probably find yourself either re-writing Python portions, or at least deprecating them as legacy and eventually migrating to some other new greenfield thing. I can't imagine any sane reason to migrate a Java or .NET project in the opposite direction.