I tried artix (not antix) archlinux systemdless based distro mostly out of curiosity a few weeks ago as I wanted to repurpose an old computer. I was also curious of systemd's memory overhead as I've seen report of people running a base kde with little memory usage on slackware compared to other distros. Turns out that writing a service definition for runit is even less complicated than for systemd. It might not be as flexible though but I didn't reach the point when I needed those options yet.
So for now I am living happily without systemd in at least one computer at my home and my quality of life hasn't changed at all, it just remembers me it is different the few times I type systemctl or journalctl out of habit.