"D minor: Melancholy womanliness, the spleen and humours brood."
-Christian Schubart, 1778
"It's part of a trilogy, really-- a musical trilogy that I'm doing in d minor, which I find is the saddest of all keys. I don't know why, but it makes people weep instantly."
-Nigel Tufnel playing "Lick My Love Pump" in This is Spinal Tap[1], 1984
Also...
"C major: Completely pure. Its character is: innocence, simplicity, naïvety, children’s talk."
... will persist as long as C major consists of a) the white keys on the instrument of the piano and b) the key in modern notation that doesn't require any sharps or flats in its key signature.
1: FYI-- Christopher Guest appears to actually be playing in d minor for that moment in the movie.