Honestly curious, do you have examples or thoughts of what this might look like? What is the core primitive upon which you want to build that is zero config but highly scalable?
That said, check out Nats.io. It's basically just a messaging system but it's beautifully abstracted, horizontally scalable and runs locally from a small binary. It largely removes the need for much middleware like load balancers. They've also recently added persistence features for streams and KV stores.
It doesn't solve every problem but I do think a message system is a very good core abstraction to build other things on top of.