At work I regularly edit files on 10-15 remote machines. But I never ssh to them and run an editor. Instead I'll just visit them through TRAMP, run Magit to commit stuff that I've done etc.
Of course, sometimes I forget I'm working remotely, and hilarity ensues. The worst episode was in a recent school project. I thought "oh, I'll just finish this on the train". And then, when I got on the train, realized I had actually been working remotely. Oops.
Not only is it seamless editing, you can actually use tramp to "cd" into a directory on a remote machine using eshell.
Edit: Holy crap, it does. That's going to be useful.