Two recent books by historians explore the crisis in biological psychiatry
bostonreview.net
bostonreview.net
What alternatives are there? Therapists don't scale. If half of society could improve their life with therapy, and a therapist can treat 30 people per month over 10 years, then 1% of society have to become therapists. More therapists than teachers would be needed.
I believe that this is a huge opportunity. Like medicine, people will be willing to pay anything to be happy. The biggest problem apart from developing a cure will be getting heard. The market will be flooded with enticing apps and a most likely bitter medicine will be a tough sell.
Personally, I think we need to lower the barrier of entry for people to become therapists, and streamline the whole patient intake process. It's not like the quality is all that great with existing barriers, there are PhDs out there actively harming patients-- one kept trying to push Jesus on me when part of what I was dealing with was childhood religious trauma and the difficulties of restructuring my world view as a nonbeliever, an absolute breach of ethics.
We need to make it easier for people to try out multiple therapists until they find one that's a good match for them, and part of that is increasing the supply of therapists. Unfortunately I'm not sure a chatbot is ever going to quite do it except for in the simplest & most clear cut cases, the mental tangles we can get into really require general intelligence to grapple with.
The real problem, IMHO, is we've built an inhumane economic system that causes tremendous stress over the psyche of the individual. Instead of optimizing for wellbeing,we optimize for GDP, this is a pretty poor proxy. A more humane and tolerant society, with less hyper stimulating culture could reduce the need for more therapists. But of course this is an ideal, I don't know how to get there, but it seems to me unleashing therapists into the wild, while streamlining out the ethical and self regulation that come with the guild structure is a terrible idea.
> Do you really think lowering the bar is a good idea?
How much lower can the bar go? The "ethical and self regulation" you describe is all too often nonexistent. If my experiences - and many others I've read about - are any indication, the situation couldn't be much worse. There are certified professionals doing everything from actively pushing religion to making a cynical game out of how fast they can pigeonhole your 'symptoms' into a checklist so they can prescribe the currently most marketed drug for that DSM entry. Then they tell you to report back in two months.
Just having someone to talk your shit out with regularly who doesn't judge too much and has knowledge of practical solutions for common stressors would be a vast improvement over the 'care' all too many are currently receiving. The guidelines for providing simpler care like this can be clear & concise, and we have better tools now for filtering out bad actors. I see more reasons to continue advocating for such an approach than not at this point.
It’s all economic pressure in the end.
AI chatbots are just the natural conclusion.
An old engineering axiom is: "If you can't build it, you don't really understand it"
This leads me to ask, will we only understand the human mind after we learn how to build one or two?
Notwithstanding the question, can a network with X neurons fully comprehend a network with X neurons?
Depends on the definition of understand. If you mean complete and faithful reproduction then maybe not. At least in one mind. Definitely a set of N minds with X-1 neurons can together understand the whole of X neurons if each simulates under given conditions or subsets of the whole.
The mind also probably has a degree of fractal self similarity in its structure and understanding a part gives a representation of the whole.
I so love this words, especially I love to read that in the middle of my reading of Kuhn's "Structure of scientific revolutions" book because that book lets me clearly visualize of what crisis in psychiatry is being waited for.
Everyone's different, but SSRIs are a hard no for me.
The crisis is societal argues the author, it's not really about the drugs. The drugs might be effective (and a lot of evidence suggests they're not really all that effective) but in our society even if they were. They would probably be behind paywalls and only accessible to rich people.
I've recently immigrated to Australia, trying to seek mental health help here has been a huge struggle and it's funny because you'd think for people with mental health problems to find a solution should be really easy. Imagine you have an accident and one of your legs stops working and the only way to get to the doctor is by walking; that's how it feels. To my australian native friends the situation has not been much easier, recently a friend was in the hospital on a suicide attempt and not only they were discharged fairly quickly but the only support they got was with a completely apathetic doctor.
Mental health is a big business and there is no interest in solving it, because as it says in the article, the biggest crisis in psychiatry is that there is no crisis in psychiatry.
I'm tired of people.
I feel the antiwork movement is starting to become the shelter of people with depression who are not being treated like they have a handicap.
I'm glad I don't have a career, because my health would have crashed of I had one.
Lots of vegan activism - grows animals on farms or trades in that sector.
Pro-Peace and cultural sector activism. Produces weapons.
Greenpeace? Usually chemical dumps or other environment damage.
Virulent Patriotism? Usually exploits cheap labor & conditions abroad.
List goes on.
The more desperate the cooperate souls peddling their convictions to "outside strangers", the more morally rotten the business usually is.
Just a observation.
> "The oft-cited claim, for example, that schizophrenia has a genetic basis has failed to pass scientific muster. As Scull discusses, after failing to find a Mendelian set of genes that could explain schizophrenia, researchers in the 2000s pinned their hopes on new genome-wide association studies (GWAS) that could investigate hundreds of thousands of base pairs in the search for genetic linkages to psychiatric disorders. But GWAS studies have not revealed a clear genetic basis for schizophrenia (or bipolar disorder, for that matter). While combining hundreds of genetic sites can help explain, at best, 8 percent of the observed variance of schizophrenia, it is still possible for an individual to have many of these genetic variations without developing the disease."
There might be some influence - for example, someone born with genetic immunological defects is likely to be more susceptible to various infectious diseases, and there might be some kind of brain development issue that means that some people are less able to cope with high levels of stress, disappointment, trauma and so on - but the claim that this outcome is somehow ordained at birth is nonsensical.
All in all, the science of mental disorders today could be compared to the science of infectious disease in say, 1890 - they didn't have much in the way of understanding of core mechanisms, even if some approaches (surgical sterilization, rigorous post-operative hygiene, etc.) were being shown to reduce mortality.
Probably the most promising tools in this regard are the use of psychedelics under controlled settings to improve outcomes, but even here, the research is basically in its infancy due to the socio-governmental paranoia over these substances.
What's more realistic to me -- and what I tried to get colleagues to do for years -- is a focus on polygenic risk, where numerous genes have small effect. This research has been more fruitful, but again, it's overhyped and oversimplified (the article mentions this too, briefly). The problem isn't with the idea of genetic influences on mental illness, especially severe mental illness, it's the way that academic research occurs in general.
The truth is, the most likely genetic explanation (which will only be a small part of the pie) -- the one that's been the case all along -- is some combination of polygenic influence, involving some complex cascade of genetic effects, along with very rare mutations occurring within single individuals or families. There's also probably lots about genetics and genetic expression we are totally wrong about in general.
I'm deeply sympathetic with the articles' arguments. Modern psychiatry has really lost its way and has neglected more psychosocial, systems-level explanations, along with things like chemical and microbiological exposures. I myself have written critiques of popular psychiatric genetic positions.
However, I think the underlying problems stem from wanting to shoehorn behavioral science into to some model where it doesn't fit. Typically this is physics or chemistry, or molecular biology. It's not that. It's kind of like that, but not the same. It's also kinda like economics, and kind of like infectious disease science, and kinda like computer science, but not quite like any of those things. But people want to oversimplify it nonetheless, and it becomes this all-or-nothing argument, between the "brainless" and "mindless", and you're not allowed to take some integrative position. Then you get into people in say, physics, complaining that because it's not that it's not scientific, which is also not true. There's just a lot of politics and pendulums swinging back and forth.
Combine this with academic fad-chasing and the funding nonsense that fuels that fire, and you have a recipe for disaster. It's like layers of people wanting to oversimplify things for attention, combined with some kind of narcissistic vulnerability with people wanting to prove they're "real scientists" or "real physicians" and in the end people with problems just end up becoming pawns in this political back-and-forth.
I'm happy to see these articles, but also a little frustrated because although their underlying arguments are on-point, they kind of end up perpetuating the same problems. Yes, part of the problem is that genes just aren't the end-all-be-all explanation for behavior. But part of the problem is we just don't know very much right now. So what will happen is the biopsychiatrists will retort with some new method or R-squared that refutes the specific points, but not the underlying message. And the process will just go round and round.
Some of this is maybe true of academics in general -- oversimplfying things to get attention -- but some of it is made worse by the field not having some consensual agreement that behavior is really complex and not likely to be reducible to anything simple.
There's no unambiguous physical test for schizophrenia that I've ever heard of, it's just things like patients having auditory hallucinations and so on. There's no known mechanistic pathway (i.e. there's no known defective proteins that the genes express that somehow mess up the auditory pathway in the brain causing such hallucinations). It really sounds more like a mis-wiring-of-neurons type of thing that develops over time in the person, due to external pressures that they're unable to cope with.
Now with infectious disease, there is a great mystery still - out of a thousand people exposed to the same level of the same pathogen, some get sick and some don't. Some of this is explained by previous immunological exposure, but a lot isn't. Some of it is probably genetic in that one's in-born complement of immunological genes likely results in increased resistance or sensitivity to viral and bacterial proteins used to target cells.
What I'd guess here is that people just don't want to admit that mental illness is more of a social problem than a biological one, due to things like mass homelessness (which could cause schizophrenic breaks), poor parenting (which parents would rather blame on 'bad genes' rather than their own personal failures), etc. Of course, the same can be said of the prevalence of infectious disease due to poor public health regimes, contaminated food supplies, etc.
Jiddu Krishnamurti
We've solved so many problems that afflicted humanity for thousands of years in the past 200 years. So why not this one? I guess because, as the article says, to solve this problem we actually need to change society as a whole.
I don’t want to develop my sociopathy to the level required to be mistaken for acceptable in what passes for society today.
I'd agree that capitalism has a tendency of rewarding sociopathy, but there's no requirement to be an amoral asshole to be accepted by your community - in fact, it often prevents it.
My experience during the Christchurch earthquakes where people risked their lives to save complete strangers is what convinced me that most people are inherently decent, and I'm not sure a society made up of mostly decent people could become as cruel as you suggest.
It does not mean that if you're low-functioning in daily life, you get to blame climate change/economic inequality/injustice/whatever. Refusal to take responsibility for one's behavior is always a sign of lack of emotional health.
have you ever heard of an eastern philosopher who didn't think western civilization was profoundly sick??
it's deeply immoral that we force kids to sit in chairs for hours a day, and then diagnose them with "the ADHDs" when they don't like it. but we could multiple examples endlessly...
It is! I suppose because of its dubious origin. First attribution seems to be from Mark Vonnegut in The Eden Express. Did you read the book, or where did you learn what it _actually_ refers to?
But basic logic dictates that the quote (which is apocryphal) means that we cannot deduce that we are healthy simply because we are well-adjusted to society, if that society is sick. It does not say that psychiatric illness is rooted in societal or social problems. And empirically, proponents of the quote (theosophists and Buddhists) also rarely use it to refer to actual psychiatric illness, but rather to moral compasses, values, and overall behavior.
I doubt you'll find many Buddhists parrot the "I'm only depressed because of how messed up society is" line that you often see on the web, since Buddhism explicitly preaches self-transformation.
Quite an informal fallacy / strawman you have there, whoever said it was?
I was particularly drawn in by the idea of the Soteria approach [https://en.wikipedia.org/wiki/Soteria_(psychiatric_treatment...].
https://news.ycombinator.com/item?id=33186046
as does the fact that some drugs show benefit. That Big Pharma perverted the research goals does not mean this is no longer a good avenue to explore.
@debihope (Boosted by William Gibson)
I decided I'd turn it into a blog post and have posted it for discussion here: https://news.ycombinator.com/item?id=33201781
Here's it is as a comment:
This is a response to an article currently being discussed on Hacker News [Two recent books by historians explore the crisis in biological psychiatry, originally titled Mental Illness Is Not in Your Head]. I believe that the, now replaced, catchy headline of the article is not correct. I believe mental health is in your head, but this does not mean that mental health is controllable through altering neurotransmitters (or in fact altering any specific biological process).
~All mental health issues use the same biological structures[1]. A structure which interprets the emotional dynamic of the situation you are currently in. Another structure which reactivates the emotional memory you have associated with that dynamic.
Most likely the same mechanism is used for both happy and unhappy paths:
# Happy paths:
If you grew up with a loving (but not overwhelmingly loving) and calm family, your unconscious association between the emotional dynamic of a situation you are in, and the emotional memory associated with it are positive. These could range from: "Everyone is having fun right now, I can relax and have fun too!", to "That person did something that made me uncomfortable, I know it's safe to express my needs and feelings, so I can communicate calmly to the person who upset me how I their behaviour made me feel".
# Unhappy paths:
If you grew up with caregivers who were stressed by certain situations, your unconscious association between the emotional dynamic of a situation you are in, and the emotional memory/requirements associated with it will contain protective responses. These could range from: "Everyone seems to having fun right now... but everyone got so stressed out when I was anything other than calm and happy when I was young, I better keep all my stressed feelings hidden inside, and be act like I'm happy and having fun too - even if something is going on for me which means deep down I'm not feeling good", to "That person did something that made me uncomfortable. Everyone go angry so quickly when I was little, that I’m sure this person will get really angry too if I say anything to them. I will just pretend that I’m ok with what they did.” This list goes on and on, and will depend on the subtle dynamics of the relationships you were raised in.
You will notice that in the happy paths there is not a separation between your external world and your internal worlds, whereas in the unhappy paths there is this split. This split is uncomfortable and it is lonely. It requires a tense form of control that the person on the happy path doesn’t need to apply to themselves.
# Things get worse […before they get better?]
I’m sure a bit of you related to the unhappy paths that I described. That is because we all have them. One of the biological survival mechanisms we have as highly dependent infants is to bend our emotional responses into ones which mean we get what we need from our caregivers.
This is such a common requirement for making it through infancy that the human is built to shed these leant emotional shackles. I am in a controversial minority within psychotherapy that believes that the precise diagnosis of these emotional shackles is the function of dreaming (https://psyarxiv.com/k6trz).
Getting rid of an emotional shackle is not complicated when it is clearly visible. It is not particularly pleasant, but you simply have to unlearn the fear by facing up to it. If you notice you keep your stressed feelings inside, you’ll need to find the courage to start opening up. If you are not setting boundaries when you feel yours are getting trodden on, you need to find the courage to start having those (initially) awkward conversations. The same is true for whatever unuseful emotional conditioning you are trying to get free from.
The mechanism behind this approach is very simple. We are extremely scared of facing these learnt fears (the type and level of fear we typically[2] only know in infancy). When we repeatedly face these fears and survive they are very quickly unlearned from the brain. It is highly inefficient for the brain to keep a fear in place that we now know (at an experiential, not only cognitive, level) to be superfluous, and the brain does not seem to want to do this.
But what happens if no one is there to help you work our your emotional shackles and you are left to suffer their isolating consequences on your own? Again, I am in a bit of a controversial minority of the mental health community, but I believe it is the useful response that mental health symptoms should worsen.
If things worsen both you and others begin to notice that something is wrong. If they notice something is wrong, there is an increased likelihood that you will get the emotional care that might lead you to successfully removing your emotional shackles; reducing your stress and isolation. Many people start treating their mental health because things have gotten bad, but the treatment (the process of discovering and facing up to unconscious fears) doesn’t need to stop when you return to your base level.
In summary, I think there is a strong component of mental illness that is very much within our own heads. Because the happy and unhappy paths of mental illness use the same structural processes we cannot force a change at the biological level. Instead we have to explore, challenge and ultimately change the underlying emotional memories that are elicited in the structural processes. From my personal experience, this causes the greatest improvement to our mental health/reduces our “mental illness”.
[1] I'm aware that I am talking with one of two layers of abstraction. I'm not talking about the specific parts of the brain, but these processes are consistent in all of us.
[2] Stressful situations we experience as adults that cause PTSD are ones where our emotional processing of the situation we are going through mimics our childlike experience. The experience is overwhelming.
> "The fact is, if we didn’t have such a fucked-up society, I’d be out of a job." ... As historian Joanna Radin encouraged me to discuss in my undergraduate course on the History of Drugs, the question is not only, What is the right drug for me?, but also: What would the world have to look like for me not to need drugs at all?
He stops short of really exploring this concept. I'll paraphrase an old comment of mine:
Are you ready for me to diagnose your totally normal reaction to our shitty society as mental illness so I can get you addicted to mind altering drugs for the rest of your life? https://imgur.com/Jb1mJyx
Or as the social critic Dr. Ted Kaczynski said, "Imagine a society that subjects people to conditions that make them terribly unhappy then gives them the drugs to take away their unhappiness. Science fiction? It is already happening to some extent in our own society. Instead of removing the conditions that make people depressed modern society gives them antidepressant drugs. In effect antidepressants are a means of modifying an individual's internal state in such a way as to enable him to tolerate social conditions that he would otherwise find intolerable."
The problem is, this is the only life most of us have lived, and so we cannot imagine it otherwise, like a fish who cannot conceive of a world without water, or even that water is the medium surrounding it. If our entire society is causing this, then what can we do? Wage slavery, oligarchy, attention theft by tech companies, disintegration of community from various causes. Life for so many people is crawling through glass Monday through Friday, then getting shitfaced on the weekend. Is that happiness?
Oh I know you can give a wishlist of things you want society to be; I bet you can't even begin to describe how you achieve it. No one ever does. The only method ever given is "revolution and then New Soviet Man". Every method is a restatement of those six words in longer format.
Sry, non native english speaker... but a broader view... ^^
Hint; Scotland has both universal healthcare and free higher education and also the highest drug deaths per person in Europe - or close to the highest.
Just because universal healthcare and higher education are offered does not mean they equate to drug deaths. That's a bullshit conclusion to draw and likely is a result of many other policy/societal factors.
And absolutely they will say society is sick, but wtf does that have to do with offering universal healthcare and higher education? Of course society will always be fucked in one way or another, but measures should be taken to improve quality of life for all in an attempt to make it more bearable and hopefully would contribute to finding solutions to the issues society faces
> Stirner's egoism argues that individuals are impossible to fully comprehend, as no understanding of the self can adequately describe the fullness of experience.
> He believed that everyone was propelled by their own egoism and desires and that those who accepted this — as willing egoists — could freely live their individual desires, while those who did not — as unwilling egoists — will falsely believe they are fulfilling another cause while they are secretly fulfilling their own desires for happiness and security. The willing egoist would see that they could act freely, unbound from obedience to sacred but artificial truths like law, rights, morality, and religion.
> Stirner proposes that most commonly accepted social institutions — including the notion of state, property as a right, natural rights in general and the very notion of society — were mere illusions.
> He advocated egoism and a form of amoralism in which individuals would unite in Unions of egoists only when it was in their self-interest to do so. For him, property simply comes about through might, saying: "Whoever knows how to take and to defend the thing, to him belongs [property]."
> Stirner considers the world and everything in it, including other persons, available to one's taking or use without moral constraint and that rights do not exist in regard to objects and people at all. He sees no rationality in taking the interests of others into account unless doing so furthers one's self-interest, which he believes is the only legitimate reason for acting.
https://en.wikipedia.org/wiki/Max_Stirner
---
Isn't that what we already have, a profoundly selfish society?
I don't see myself in his system - I'm neither a willing nor unwilling egoist. I consider my self-interest to be part of a larger "collective self-interest" of humanity and the ecology of life. But perhaps that's my false belief and I'm only "secretly fulfilling [my] desires for happiness and security". It could be, since the happiness of the collective supports and contributes to my personal happiness.
As a way to illustrate this, unmoderated online forums tend to adopt the same tone of voice and type of humor as 4chan. If there was true intellectual freedom without restraints, there would be more tonal diversity, but what instead ends up happening is that the type of people who would adopt Stirner's worldview would end up behaving in very similar ways to one another.
yknow , I agree with your broad points -- I even agree with the sarcastic tone you used to convey the line, but the families of those murdered or injured by Ted Kaczynski would probably prefer the title murderer/arsonist/terrorist.. even inmate.
Most folks would probably prefer that the most infamous title be used when speaking about those that society has deemed to be of ill repute.
'Spiritualist Genghis Khan' sounds weird. So does 'music aficionado and critic Charles Manson'.
It's a grim take, but the condemnation offered by the legal process is one of the things that helps the victims of a crime cope. In other words, the social branding of 'murderer' or 'convict' onto the person charged with the crime is also part of the justice offered to the victims via the legal system -- to ignore that the social title and distinction of the person has been affected by their transition to 'convict' status is to ignore a facet of what the prosecution was attempting to achieve for the sake of the victims.
> to ignore that the social title and distinction of the person has been affected by their transition to 'convict' status is to ignore a facet of what the prosecution was attempting to achieve for the sake of the victims.
why on earth should that take precedence over everything else?
> Or as the social critic Dr. Ted Kaczynski
Whose doctorate is in mathematics.
Imo a lot of what Kaczynski says is actually very well thought out and there are multiple other philosophers and thinkers that have come to similar conclusions or have pointed similar problems with society.
If you had read that statement without reading who it was that said it, what would you have thought about it?
Reducing the multiple potential causes of depression to "society is bad" does a dramatic disservice to people who suffer it.
[0]: https://www.goodreads.com/quotes/586570-there-are-essentiall...
Humpty Dumpty had a great fall.
All the king’s horses and all the king’s men
Couldn’t put Humpty together again.
Not even with drugs. That's how the mind works. Build something new in your head; don't try to reclaim what's lost with chemical glue.
The result TLDR: everything we measured about individuals is heritable.
We are physical beings. All the processes happening inside us are mediated through chemicals. Most are assembled according to a building plans encoded in your genes and the building blocks come from your environment. Then obviously as the brain is the command centre of the body, it does involve the head.
Still, it doesn’t tell us much.
For all intents and purposes, we have shockingly little understanding of how the brain actually works. We know some chemicals have unexpected effects but we don’t always understand exactly how that happens. We don’t understand how memories are stored or recalled. We have some understanding of the feedback loops involved in emotion processing but that’s far from perfect. We are starting to realise that the processing happening in other organs like the digestive system have an effect on the brain but it’s not entirely clear which.
I think people generally are not humble enough regarding the level of actual knowledge we have reached in psychology and medicine.
I wouldn’t be surprised if we came to discover we had actually been missing something foundational at some point.
The mind is very close to a computer. Few people use science to develop or debug software. Even if there is a scientific model that explains why somebody feels bad, is that model enough to determine a cure?
> Understanding the undulating history of psychiatric hype and crisis is crucial today as the profession builds toward its next trend: psychedelics, already heralded as a “renaissance” and psychiatry’s “next frontier.” These two histories demonstrate that the academic and corporate pursuit of such hype [...] resulting in significant psychological and bodily harm.
this articles ignores the unfounded claim: that the real purpose of the APA was not quite to heal, not after ww2.
> We also have not had any significant breakthroughs in treatment.
They even say this, which is as nazi social control as it gets.
> psychiatrists in the 1970s who pathologized Black activism as “psychosis.”
oh, and what Bush said in the 90s? I suppose all that went into marketing, and later on (i.e. nowadays) into 'engagement' metrics for online content and so on. so, as I said, they're not trying to heal you, they're trying to make a buck same as everybody else in a capitalist society/marketplace.
now all that scientific progress is being used in an information war. as war crazy as it gets.
Which, I think, sounds very reasonable. If your work environment is toxic, the way to get better is to improve the work community, or find another community to be part of.
If you feel nothing, no emotion or no sensation in the body then that is also a felt emotion in the body as a lack of feeling.
So, three inputs.
Energy input as food/drink, how fast you breathe in. Energy output as what you do in the world and how much your muscles exert themselves.
The third input to your body is your stress response as interrupted by your brain. Stress in this case can be pain and discomfort, but also any other input or thought from your senses.
Your body doesn't know that a lion jumping out of the grass is terrifying, it just responds to your brain throwing terror seeds at it.
Your body doesn't know that seeing "23 53 34 78 and bonus number 5" means you just won the Powerball lottery, it's just responds to the your brain throwing happiness seeds at it.
Like you said, mental health can be systemic, but having bad inputs can stress you out as well. If your problem is mainly bad inputs, then you can control your response, just in a loose way rather than a tight way that we humans seem to prefer.
but you're still right, our own guts are what I had to look at in order to deal with this illness.