Sometimes alcohol overuse is indicative of metabolic problems. Their brain say 'starving, please feed me', but because of insulin resistance sugar can't get into the brain cells. Ethanol has 7 calories/gram. It gets converted into acetate, which is easily used by the brain as fuel. https://news.ycombinator.com/item?id=14085230

There was a link I found interesting, on student athletes and the '4 day hangover'... https://news.ycombinator.com/item?id=21255738

Naloxone and naltrexone can be really helpful at reducing the amount of alcohol that you can consume. Naltrexone is FDA-approved for alcohol abuse. My friend's alcohol use was under control for about 2 weeks after her treatment with naloxone. Low dose naltrexone is probably more beneficial than full-dose...

Another friend told me of how, while on naltrexone, she could have a beer, then half of a second beer, but couldn't finish the second beer. She drank to make her emotional problems go away - it was easier to stop the naltrexone than the alcohol.