Cassandra works really bad with fat nodes (lots of data on one node), and much much better with a lot of small nodes, and 100PB with 300K nodes confirms this. Scylla scales better vertically, but don't know how much.
Some comments are already comparing this to pgsql/mysql/whatever. Please don't. You can't make the same queries even though the language seems to support it.
Cassandra is good at ingesting data, bad at deleting, really really bad at anything remotely relational. Errors are almost pointless.
I'm going to point at an older comment of mine on cassandra: https://news.ycombinator.com/item?id=20430925#20432564
The takeaway should be: Yes, cassandra/scylla can be really fast and scale a lot. But it is also very probably unusable for your use case. Don't trust what the CQL language says you can do. Don't get me started on how bad the CQL language is, either.