But why? Seems silly you use the mechanism of education as a filter and make a course obnoxiously and unnecessarily difficult for that purpose. Why not... filter pre-med students by simply limiting admission into the program? The earlier you make people seriously consider things the less time they waste and headache they endure. How many practicing medicine today actually use organic chemistry regularly? Most don't at least from the pool I've worked with (surgeons, internal medicine, pharmacists, nurses, etc.). Pharmacy is the closest but most rely on database systems outside of hospital pharmacists or active researchers in drugs.