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7. Conclusions Sauna bathing is associated with many health benefits, from cardiovascular and cognitive health to physical fitness and muscle maintenance. It is generally considered safe for healthy adults and may be safe for special populations with appropriate medical supervision. Heat stress via sauna use elicits hormetic responses driven by molecular mechanisms that protect the body from damage, similar to those elicited by moderate- to vigorous-intensity exercise, and may offer a means to forestall the effects of aging and extend healthspan.