I have spent the last 12 years in the startup ecosystems in US, Europe and Asia.
Europe progressed quite a lot and now can be considered a matured one, however compared to US and sophistication of investors, deal-making and deep-tech it is still a young adult compared to the season 50 years old American veteran with scars and experience.
APAC still a teenager in that sense but with a lot of spotlight.
Different cultures, mentality, support system and also chances of making it in the end. I feel like if you have a possibility to be close to the valley, your chances of making it are probably 50% higher than anywhere else in the world and that route actually makes sense.