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Comment by sometimeshuman | Hacker News Reader

Can someone recommend where one can order a full genetic sequence currently in the US and get the raw data ? It seemed highly-regulated when I last checked and required it be order through your doctor. The article touches on this a bit how the price gets into the thousands due to markups and counseling.

Also how many full sequences would I have to get before the data is statistically sound. Since there is likely a base pair or two that will be different between the cells (maybe) and the sequencer hardware and process will likely have errors too. My gut tells me 10 to 20 but perhaps that seems like overkill since many base-pairs might be junk/repeats/irrelevant anyway and the raw data will have some confidence indication as well IIRC.

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I asked this same question not long ago and the CEO of a well known company in this same research area reached out and recommended Veritas Genomics https://veritasgenetics.com/mygenome/

I’ve yet to finish the order process but I share this here because in my research of companies providing full sequencing services I never came across them and yet they seem far more reputable than others. Current SEO for these services turns up a lot of sketchy companies.

Any idea how much this costs? The order buttons on their website are greyed out for some reason

You can remove the disabled-btn class and you'll be able to click it. The basic price is $999 and the premium price is 403'ed. A bit pricey for hobby research purposes and it isn't even clear if they are accepting orders. Why is this industry such a mess at the consumer level?

too bad they don't even let you order it... makes me question the recommendation

You should be looking for 30x coverage.

There are a number of companies that will do 30x WGS and give you the BAM file. I believe Nebula is one of them, but know there are other names out there.

Nebula most likely ship your samples to China for processing and sequencing because it's so much cheaper. While that might not be a deal breaker for some, I would personally prefer my sample not be shipped elsewhere.

Stay away from Nebula. I had such a hassle with them and after six months of complaining with mostly no response I had to threaten then with a civil suit and they finally replied "your sample was no good, here is your money back."

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