While it's not inorganic molecules (Ray is not specific about technology implementations on purpose), immunotherapy is already getting better, and this looks like one more interesting example.
While it's not inorganic molecules (Ray is not specific about technology implementations on purpose), immunotherapy is already getting better, and this looks like one more interesting example.
This number seems oddly small and specific? If aging is "cured" in humans in 12-15 years, you would expect it to be already cured today in animal models. Is there such an example where we were able to make an animal immortal?
In any case I'm skeptical for the same reasons as the parent. Until we can do it to a mouse reliably, it's at least 20 years away.
The other thing that people miss is we have cures for a whole lot of things that people still die from in many parts of the world. If this technology was available, I don't see any encouraging precedent that it would become cost effective enough in any normal time horizon to be available to normies like the rest of us.
There are 2 ways to fix the problem: have a cure for cancer or use other proteins instead of Yamanaka factors that only do partial reprogramming.
There's research going on in both direction, though the second solution could have more research in it (the $2B injection to Altos Labs by Jeff Bezos can help though).
There are competing hypotheses for what's causing aging and how it may be "cured".
Among the more "simple" ones is that aging is programmed, for some reason like to ensure genetic diversity and that new genes can get a good chance to survive and reproduce. That's the thing with young blood seemingly doing some rejuvenation on older individuals. This has not yet resulted in huge lifespan extensions of any animals. Whether this is just because the procedures needs to be tweaked a bit or the hypothesis is wrong should become clear in the next few years I think.
There are at least two ways to go about this:
1 - keep making computers smaller until they are ingestible and somehow interface with biology
2 - learn enough about existing biology to be able to re-program cells for our purposes
However, to me the most exciting type of projects are the ones that merge these approaches, like an ingestible pill shaped device containing a compartment filled with bacteria engineered for particular tasks. In one case the bacteria were made to glow in the presence of heme, and the device contains a light sensor as well as bluetooth transmitter to relay the data to the smartphone in real time. https://www.science.org/doi/10.1126/science.aas9315
As Feyman mentioned, this type of device could also be made to capture a biopsy, perform certain micro-surgeries, etc aka Swallow the Doctor.
But without even even getting to the super fancy nanorobots, it seems to me there is a lot of low-hanging fruit in simply chemically modifying or repackaging existing drugs for tissue-specific application. This would enable increasing the dosage of existing medication without increasing side effects. That seems like something that could happen by 2030 and it would revolutionize medicine.