well yeah, uprights weren't built for the best sound. if you ask me, the order is mid sample < mid upright < good sample < good piano. i use keyscape, one of the better synth pianos with a massive ass sample library. i also own a 20s mason & hamlin, and there are absolutely differences.

i don't bother micing up my piano if i'm recording something electronic, but the difference is absolutely there especially for classical performances where dynamics are super important. for fun, me and a couple buddies recorded on a real c7 and keyscape's, same thing, and we all preferred the real mccoy blind tested every time.