That's be a pretty clever solution. I wonder if any case designers are brave enough to try to pitch that solution. Somewhat fits in the rising popularity of putting your tower on your desk.
> I don't understand why some extra slots have to raise the cost up 10 times
Part is market differentiation, but the other part is that you quickly run out of PCIe lanes to the CPU (especially with Intel, thanks to their market differentiation). If the mainboard manages to use no more PCIe lanes than the CPU supports, everything is simple. Once you add more or bigger PCIe slots, more M2 slots or more USB3 ports, the mainboard has to include a fairly expensive PCIe switch to turn few lanes into more.