Anecdotal, but I did not experience this at all. I bootstrapped a B2B SaaS company to exit, worked for the acquiring company for two years, and then applied to (and got offers from) ~5 companies in the startup and FAANG-adjacent space. Not a single one seemed to consider my experience negatively. In fact, most commented on it positively and it seemed to help make the initial phone screen rounds go quite well (recruiters and hiring managers were really drawn to asking about my experience as a founder).