It's possible that one day Firebug will be totally superceeded. It's possible that both tools will have separate audiences for some time. It's possible that the new native tools will be a total flop (although I have a vested interest in making sure that doesn't happen!)
Heck, if the basic functionality is there then Firebug can be written to take advantage of those APIs, which would be a win all round.
Any input is appreciated, please post here: https://groups.google.com/forum/#!forum/firebug
Honza
As mkopinsky points out it's sometimes hard to tell what really leaks memory. I can tell the same thing as he, but I think it has been improved a lot lately. Sometimes I had after some time working around 1.5GB Memory usage, but this is better now.