It must not fly over people or vehicles with people in them.
State privacy laws may provide restrictions above FAA airspace guidelines.
Drone operators could get in trouble for taking off or landing on private property.
Source: I'm a commercial license holder and have done some personal research into what's ok for the purposes of drone mapping.
Edit: That appears to be in Class B airspace, starting at 680 feet above mean sea level. Ground level there appears to be 250 feet above sea level, so flying a drone means you could go 430 feet above ground level before you do something the FAA gets real angry about.
As a drone operator, you can fly 400 feet above the ground OR 400 feet above any structure you are surveying. So it's something this pilot may want to be very, very careful about.