Unnecessarily long article, but I appreciate it.
I take 20+ something supplements every day, half of which are intended to improve cognition. (You can see most of them at http://supplementwiki.org/Supplement_Wiki:Todo_List ) I attest to their utility, however their cumulative effect is actually really mild. If anyone's taken adderall or other stimulants before, you know it kicks in and wears off really quick. With nootropics you'd actually want to take long term, it's almost as if they don't work. After a few months, however, you notice you learn and observe more quickly and your speech and interactions become a lot easier and articulate.
Also: ImmInst (for Immortality Institute) is now known as Longecity, see http://longecity.org/forum