However I also suspect that as you get older your vein structures change and theres probably a time in your 30s-50s where you biology changes and you start adsorbing more cholesterol (from fat) onto your arteries that cause CVD.
However I also suspect that as you get older your vein structures change and theres probably a time in your 30s-50s where you biology changes and you start adsorbing more cholesterol (from fat) onto your arteries that cause CVD.
Atherosclerosis is found ONLY in largest arteries where the blood pressure is highest and where the blood vessel splits into 2 because there the fluid (blood) flow gets distorted and slight vortexes are created.
Those vortexes then cause the blood pressure to be exerted perpendiculary to the blood vessel wall at artery junctions.
It's the high blood pressure + vortices + damaged blood vessel lining that PUSHES particles into the blood vessel walls.
There is no atherosclerosis in veins (because those carry blood back to the heart at lower pressure).
If fats would "attach" to the blood vessels you'd expect atherosclerosis even in veins, but you never get it there.
Also: atherosclerotic plaque is only 0.5% cholesterol and 0.5% fat. The other 99% is "scar tissue" and other stuff.
It's time to put this silly "fat attaches to blood vessel walls" thing to rest, it's 2022.
You might wish to check out Bart Kay's youtube channel, he explains it nicely there.
Smoking? Irregular exercise?
The real question is what causes the blood vessel walls to get damaged (since the scar tissue is the healing response of the body, but if the damage keeps on piling it grows too much instead of being gradually reduced over time).
The problem is that there are millions of causes of inflamation etc...
In general the best answer is "modern diet" full of sugars + fat at the same time.
Carbs in high doses are poisonus, there is a reason the the lives of diabetics end in limb amputation, blindness and severe pain due to nerve damage due to sugar destroying them from the inside out...
Agree biggest concern is what is causing damage to the arterial walls. To be fair --> fat + cholesterol attach to the wall in order to repair the arterial wall so, fat does attach to the wall.
I'm guessing the scar tissue cell matter attaches to the cholesterol+fat which is trying to repair the wall.