Oh come on. Why do programmers like to exaggerate things in plain English? Maybe because naming variables using words like "massive", "colossal", or "monumental" won't fly in a programming language?
There's no "massive amount of toolchain pain". Did you use Clojure last time in 2012 or something?
You can literally just install Clojure and start writing Clojure programs in your shell.
Well, if you want something personalized or project-specific, then of course you'd have to learn some stuff, that's not gonna change for any general-purpose programming language. And I don't know how you can get more general purpose than Clojure - it can run on JVM; on JavaScript platform; on .NET CLR; in Flutter; can do R and Python interop, you can write bash scripts using Babashka and nbb.
The days when you needed to learn Emacs to use Clojure are well in the past. Today you can write Clojure in Vim, VSCode, IntelliJ, Atom, Sublime, Nightcode, Emacs and even Eclipse.