I'm not a neuroscientist so I won't argue that point. I think as far as self-improvement and personal growth is concerned, however it seems that at least on a surface level that people can alter their behavior. Again, whether they are hard-wired to do so because of brain structure I don't know.

Your belief is a self-fulfilling prophecy. You won't change because you think it's not even worth trying.

And it works both ways - if you believe you can change in a meaningful way, you will.

See my post elsewhere in this discussion with two books on optimism and self-theories.