One of the purposes of a scroll bar is to indicate how long (and/or wide) some piece of content is relative to your window. Another purpose is to indicate your current X/Y position within some piece of content.
Both of those purposes are completely broken with the use of infinite scrolling, because the length (and/or width) of the content keeps changing (increasing) and thus your position in that content also keeps changing.
I shouldn't have to explain how terrible this is from both accessibility and simple practicality standpoints.