We've been using this approach for a long time in a B2B setting. The fallback to a file picker is really elegant for our use cases wherein some users operate on an old-school desktop PC rather than a mobile device.

The state of the modern web is pretty incredible now. There really isn't any kind of application that I would feel uncomfortable building this way in 2022.

For me, native has evolved into pure overhead (unless you need to light up some shiny device-specific feature that will inevitably become deprecated within 2-3 years). I also understand those who believe their product's main selling point is that it exists as an offering in the various app stores. For us, we actually have a value proposition beyond "it has a native app icon".

If I had to attribute my confidence in the web to any one specific aspect, it would have to be CSS grid by a very wide margin. Realizing that I could achieve the exact layout I want on any range of viewport without having to pull down a 3rd party dependency was a huge step for me.