Sure, I think some of the latest USB standards should be able to support that while at the same time providing 4K@60Hz. But I'd also like the monitor to support higher resolutions, too.
The monitors with USB-C charging that I've seen (eg X34GS) have really bad coil whine if you use them for charging... which is sort of like the main point here. and beyond that, it's only 89W, what happens if you want a 140W charger? what happens if you want 10gbe and the monitor doesn't have that? what happens if the thunderbolt part of the monitor is poorly implemented or has problems? thunderbolt is known for being finicky and do you want to trust monitor companies to get it right, when they can't even make a monitor that doesn't coil whine while charging?
and on the flip side... what if you want to upgrade your monitor, or it fails/breaks? or what if you want to upgrade to something better? the monitors with a good dock implementation won't necessarily be exactly what you want, and it certainly will be expensive compared to picking a dock+monitor separately.
it's very attractive in a sterile product-designer sense to have the dock built into the monitor, but dock+monitor is nearly as clean and gives you a LOT more flexibility and reliability in a practical sense. If anything I'd go the other direction and have the monitor powered off a usb-c from the dock lol.
as far as general cleanliness, one of these years I'm gonna cut a hole in my wall and drop some cables to the basement with TB3 or DP 1.4 active fiber cables (not electrical cable so fire code ignores it) and use a TB4 dock as a header for my desktop in the basement, so it will be super clean. You can even run power cables in the walls (technically you probably need this to be speaker wire to get CL2 fire rating) and eliminate all cables except for a couple running to the dock/monitor through the walls. Get a monitor arm for your desk and you can lift everything up and clean it all, etc. Would be super nice, I'm tired of cables everywhere and my desktop dumping heat in my office.
(don't do wallmount arms though... tried that and didn't have very good results because the monitor arm really works best going straight forward and doesn't give you a lot of motion laterally. With a desk-mount arm you can put it where it needs to be, with a wall arm you have to put it on a stud and you can't really move it laterally very much, so if the stud isn't exactly where you want it, you almost have to move the desk to fit the mount, didn't work well.)
The former seems more and more common among monitors, so it should be easier to find the kind of monitor you want.
But it's also true that it's probable for your connectivity needs to change before you want to change the monitor.