I think Thiel is frustrated that innovation in this country has shifted from science and technology to mobile phones and banner ads. The best and brightest are working in the wrong industry. Instead of researching alternative energy, space travel, health, etc, we're researching thinner smartphones with better battery life and more effective ways to sell ads.
Makes me wonder how far along we'd be, technologically, if YouTube and Facebook had never been invented... We're just too distracted now. Maybe Fermi's Paradox can be explained by alien civilisations becoming too busy posting cat videos on Twitter to invent inter-stellar travel.