Indeed. Interestingly, psychedelics (mushrooms, LSD) work wonderfully for me, but cannabis is typically a bad experience (anxiety, nausea, no attention span, racing thoughts). Every brain is wired differently.
manic symptoms vs. depressive symptoms can definitely be linked to strain, and the balance of constituent psychoactives...of which there are plenty. ask a reputable bud tender for sleepy weed and i wager your experience might be more pleasant.
If we’re works for you, great. If it doesn’t, something else will.