I have to flip it between 59.95Hz and 60 Hz in the windows advanced settings, changing that setting basically makes the monitor re-initialize and then everything is fine. It happens every time I wake the monitor from sleep (ie: my computer rarely, if ever goes to sleep, but the monitors will turn off after 10 minutes of inactivity)
This only really happens with games. DirectX or Vulcan doesnt matter. Doesnt affect things like youtube, plex etc.
But any game in fullscreen or borderless windows on that screen, i have to basically just change that setting back and forth to keep my sanity.