At NASA I wrote a set of Python scripts to help with planning and telemetry for a Mars mission. I had to convert a lot of time data points between UTC and a Mars timezone/clock (specific to the rover itself). There was an officially blessed tool written in Java that ran from the command line for time conversion. It was too slow to call out for each data point, so I figured it would be generally useful to port the conversion to Python.

First I dug into the Java source, which it turned out called out to a C library. I believe the C library linked out to a Fortran library. It was a lot more complicated than a simple scale and calendar - there were corrections for special and general relativity. Converting times actually required propagating orbits and estimating some non-closed-form quantities. In the end is was more work than it was worth, so we just did an approximation ("only" good to a few milliseconds - fine for our case).

So I guess item number 100 on this list should be "time is experienced the same way by all observers" and maybe 101 "simultaneity depends on the reference frame" :)