Think really hard about switching jobs now. If you do, have liquid reserves to fall back on(cash or cash equivalents, T-Bills, not stocks), and pick a company with good cash flow.
I understand folks who have ridden out the last two recessions and will tell you you'll be fine, and you probably will be, but don't be hasty right now. A lot of big companies are going to be under growth pressures in the next few quarters and one easy way to cut expenses is to fire people.