Practically this means costs of nuclear power plants are very high, as you have to over-engineer them relative to other power sources. Natural gas and coal plant accidents are relatively common, for example; similarly oil refineries suffer fires on a regular basis. However, Texas City (site of a major BP disaster in 2005) is not currently a 100-year no-go-zone. Here's a 5-minute video on how that played out:
https://www.youtube.com/watch?v=c9JY3eT4cdM
Point being, there's no way to reduce nuclear power upfront costs without also introducing unacceptable risks, and that's a major reason why nuclear isn't going to replace fossil fuels on a global scale (along with the uranium ore to fuel rod to waste pile supply chain issues,decommissioning costs, etc.)
There's no catastrophic failure mode for a solar/wind/storage based grid, and that's one of several reasons why nuclear will remain little more than a niche provider.