Writing behaviour flows can end in beautiful blocks of easy to understand operations. However, as these get more complex and you need to combine multiple data streams, logic is scattered all over a module.
Refactoring data-flows that go through multiple modules is a huge hassle. Sometimes, we would spend hours just refactoring data-passing, wrapping and unwrapping and tests surrounding modules, because we needed to pass some additional values.
It doesn't help that you have to set up all behaviours at setup time, which means the code is mixed with one-time setup code which regularly confused people working on the projects as to what is run at startup time and what is run per-event.
Debugging itself was mostly hampered by the libraries that we used not providing adequate tools for the job but even if they did, it was a lot more difficult to reason about compared to something like async/await based code or callback chains.
I can imagine FRP works better in purely functional languages but implementing FRP paradigms in general purpose languages - especially when interfacing with non-functional code, which is often necessary - has led to nothing but trouble for me.