A bit of internet trivia is the oz.au domain. In the late 1980s, the Australian universities were connected in a network with names ending .oz.
When the TLD .au arrived, .oz was renamed .oz.au. So my email address at Elec Engineering at Melbourne University was <name>@ee.mu.oz.au.
And then a few years later, the third-level structure got formalised. Melbourne Uni, for instance, switched from mu.oz.au to unimelb.edu.au.
I for one missed the typographic economy of the ee.mu.oz.au domain.
None of this really matters, of course, except that a sensibly designed structure with a clear underlying rationale, and historical context for a small number of exceptions, makes everything easier to understand :)