People have been making this argument for as long as I've been alive, and for the majority of non technical businesses, it's less true than ever... Malware is less prevalent, and MS Office remains pretty supreme.
Except for Excel. Excel is truly amazing software and there isn't anything to replace it for many people. I use Python now for my number-crunching, but I used to use Excel extensively when I worked in quality assurance and didn't have access to Python. No way that LibreOffice's spreadsheet can replace it, except for the most simple of spreadsheets. At least not today.