Personally, it does! Working hard makes me hungry, also tired, but less so if I eat well. I obviously can't overclock my brain as you describe, but there is definitely a link.
Speaking of overclocking, that's what bats do. Flight takes up a lot of energy, so they have evolved systems to deal with all the byproducts, including toxic chemicals. Interestingly, this is also why they have no problem carrying what for us are deadly viruses: overclocking results in cell damage, something that bats are equipped to deal with, but it would also trigger inflammation, so bats have damped their inflammation response, but that would leave them vulnerable to infection, so they evolved a faster immune response that is able to outpace the virus, and when one of these viruses jump to humans, they have time to reproduce a lot before our immune system reacts causing a massive inflammation that ends up doing more damage than the virus itself.