I'm saying that when those strategies are applied axiomatically, there's no room to reinterpret what we know about the world because there's a general feeling that doing so will undo all scientific progress.
Take, for instance, the relativity vs. quantum mechanics debate. I'm not a physicist, but it's pretty evident that the biggest struggle of that debate is that most people want to reconcile both theories by unifying them through some other rational interpretation of the world. Whether or not that's possible remains to be proven, but a theory of everything may emerge from a completely different interpretation of the world. One that is rationally contrarian to what relativity and quantum mechanics tell us.
And this brings me back to my original argument, which is that perhaps we have the proper methods to understand the world, but we are just asking the wrong questions.