Saving a Life is Easy, But I Didn't
danshapiro.com
danshapiro.com
That actually isn't really true. Marrow donations still require anesthesia and a surgical procedure. In the interest of providing full information:
http://marrow.org/Registry_Members/Donation/Donation_FAQs.as...
http://marrow.org/Registry_Members/Donation/Donation_FAQs.as...
(Edit: c'mon folks...why in the world would you vote this down? It's important information to know if you're going to be a donor.)
PBSC donation is a non-surgical procedure done in an outpatient clinic. PBSC donors receive daily injections of a drug called filgrastim for five days, to increase the number of blood-forming cells in the bloodstream. Then, through a process called apheresis, a donor's blood is removed through a needle in one arm and passed through a machine that separates out the blood-forming cells. The remaining blood is returned to the donor through the other arm.
Speaking to the marrow.org representative, she said that these days it's about 75% PBSC (sitting in a chair watching TV), 25% outpatient surgery (which is easier now than it was 16 years ago, but still daunting).
I'm also not trying to disagree that people should donate...it's just that you really do have to have a surgical procedure if you're donating marrow. Moreover, PBSC involves a five-day injection drug regimen (filgrastim) that you need to undergo before you get to sit in the chair (http://marrow.org/Registry_Members/Donation/Donation_FAQs.as...). Either way, it's a far more involved procedure than (say) donating plasma -- which is how your post made it sound.
The FAQ also says that PBSC donation is considered "investigational" (http://marrow.org/Registry_Members/Donation/Donation_FAQs.as...), though who knows what that means. I just think people should be able to read the answers so that they know what they're doing.
I also wonder why the databases aren't as international as it should be, so a match is against the world than just a region.
Now reviving a donating is still risky, but usually it's a choice between death and some lessor risks.
Effectively zero, as onemoreact says.
The chance of becoming infected due to unsterile conditions or opportunistic infections is higher than zero, however. This page is the best I've been able to find so far:
http://www.livingdonorsonline.org/marrow/marrow5.htm
That page says you're taking about a 1 in 370 chance of serious complications:
> life-threatening complications for all marrow donors have been rare; there were 13 reported in 4,800 [0.27%, or one in 370] analyzed marrow donations.
edit: I found a small-n study that is very positive:
edit 2: I omitted the small-n study, because I found a much bigger one:
> The experience at a single institution in harvesting marrow for allogeneic transplantation on 1,270 occasions from 1,160 normal donors is presented in detail, together with an analysis of all the donor complications... Hospitalization time was three days or less for 99% of the procedures. Six donors had life-threatening complications; three of a cardiopulmonary and two of an infectious nature, and one cerebrovascular embolic episode. Significant operative site morbidity, usually transient neuropathies, occurred in ten procedures.
http://bloodjournal.hematologylibrary.org/content/64/3/630.s...
tl;dr: marrow donation carries about a 1% chance of any complications at all, and a .5% chance of life-threatening complications.
Because it's spreading misinformation that could prevent people from becoming marrow donors.
As a way of balancing this, here: http://marrow.org/Home.aspx
They'll send you a free kit. You swab your cheek, mail it back, and then you're in the registry.
Take five of your minutes and give them to somebody that needs them.
It might prevent people from becoming donors, sure, but it's not misinformation. You may think that the risks are small relative to the benefit provided, but you shouldn't pretend (or try to convince others) that there are none.
Take five of your minutes and give them to somebody that needs them.
It takes five minutes to register. It clearly takes more than that to actually donate. You're not doing anyone a service attempting to conceal this fact.
1) I'm saying to take five minutes and register as a potential donor. If you're found as a match, you're not required to donate. You then get to chose if you want to donate more of your minutes.
2) You're vastly overstating the liklihood that you'd have to undergo surgery to donate bone marrow. This is typically referred to as FUD, and is generally considered a bad thing to do.
The latter is far more more common and isn't technically donating marrow, but can be used in place of it.
A college frat boy who has had unprotected sex with a different girl every week for the past semester can give blood/marrow, but monogamous, healthy gay men can't. I don't get it.
And no, it is not for health issues because they don't turn away gay women.
Of course you could register if you want to and then if called upon show up eagerly with your partner for moral support. Then flat out ask if they are going to kill their own patients just to pretend that it is still the fifties.
Of course don't do it if they can't get a donor in time.
The problem, as I see it, is that most countries place an unreasonable bias against _all_ gay men rather than _some_ gay men. The appropriate way to handle donor screenings is to ask about sexual behavior in general, such as whether or not you are monogamous, how many partners in the past year/two years/five years, how often condoms are used, etc.
Instead, we blatantly exclude all gay men but do not exclude other high risk demographics. For example, black women are eligible despite being an extremely high risk group compared to white women (1 in 58 vs 1 in 588, respectively).
Unfortunately, the FDA is so afraid of alienating existing donors by asking them for a sexual history profile that they would rather stick to the status quo and continue excluding gays altogether.
Which could actually make sense. If (if!) it's correct that asking about sexual history would alienate existing donors, and if (if!) it would alienate enough to compromise the blood supply, it might be "safer" to keep the current rules in place instead of trying to be somehow more objectively "fair".
So, gay men and women may be treated very differently by health officials with some valid reason.
[1]The CDC actually tracks the objective category "men who have sex with men", and not the fuzzy labels "gay" and "straight".
[2]http://www.cdc.gov/nchhstp/newsroom/docs/fastfacts-msm-final...
There is probably some testing regime that could be implemented that would allow tissue and serum donation programs to be blind to sexual behavior.
http://www.cdc.gov/hiv/topics/surveillance/incidence.htm
CDC estimates MSM represent approximately 2% of the US
population, but accounted for more than 50% of all new
HIV infections annually from 2006 to 2009.
If you can drop your incidence of HIV by 50% while reducing the pool size by only 2%, you've improved the infection incidence in the pool substantially!Yeah. I thought it was implied that we were talking about that, though. I mean, even the casual reader should be able to infer that gay men do not make up anything like half the general population. That would mean there were no straight men at all.
If we have several small populations of people with a high incidence, though, I think the raw contribution is actually the right number to talk about. Consider the following thought experiment:
I have 100 people, and 6 HIV infections. 10 of the people are gay men, and 3 of them are infected. 2 of the people are female prostitutes and both of them are infected.
The general population has a 6% infection rate. The gay men have a 50% infection rate and account for 50% of the infections. The prostitutes have a 100% infection rate and account for 33% of the infections.
The exclusion of which group improves the resulting donor pool more?
If we exclude the men, we are left with 3 infections / 90 people = 3.3%. If we exclude the prostitutes, we are left with 4 infections / 98 people = 4.1%.
Even though the prostitutes have a much higher rate of infection than the gay men, excluding the men helps the final result more because they account for more of the overall infections.
Either is fine. "50% of HIV positive people are gay" is not. For all we know, there are only two HIV positive people, and one is gay and one straight. That's hardly a reason for excluding all gay people from donating...
Couldn't find all the numbers I was looking for, but it turns out 61% of infections in US are through male-to-male sexual contact. This probably translates into over 60% of HIV carriers being male and gay.
Now, if I was a guy in a position to decide things, and I could reduce by more then half the risk of HIV in transfused blood by reducing the donation pool by 7-10%... I'd do it in a heartbeat.
If you have some time you could try to calculate how many more people would get HIV if gay people would donate blood. You could subtract the people who wouldn't die because of the increase blood supply. But the result would still be positive.
The point of the whole blood donation thing is not to be politically correct, but to solve a problem. Making it politically correct, in this particular case, would mean solving the problem worse, possibly significantly worse then if we just let them do their jobs.
It's a question of perspective. You might be certain enough of your and your partner's fidelity over the last year to bet a stranger's life on it. But they aren't confident enough in a stranger's assertion of marital fidelity to bet their patient's life on it.
You seem to be saying, in essence: allowing gays to donate doubles the number of instances of transfusing HIV while only increasing the number of lives saved by 7-10% (or 20%, or 2% - it doesn't matter). But that's the wrong way to look at it. Even if 10% of all transfusions from gays resulted in an additional HIV infection (thanks to testing etc., I'd guess it'd be well below 1%), that still means that, for any given transfusion candidate, you have a 90% possibility of saving their life without transfusing HIV.
Excluding certain categories is a simple and effective administrative solutions - and doesn't really make any sense to confuse it with anything else.
> All blood gets tested and though false negatives are still possible, most infections are statistically close enough to 100% detectable after 6 months.
This kind makes irrelevant all the outrage over them accepting blood from donors who have had wildly unsafe sex over 12 months ago. At this point it's only a matter of risk management surrounding the possibility of recent infection. You may say that in that case, it shouldn't matter if you had a same-gender sexual encounter 30 years ago, but this really just boils down to statistics, and having a same-gender sexual encounter puts you in an entirely different statistical category than people who restrict themselves to strictly heterosexual encounters.
I think you both imagine that transfusions are 1 on 1. (1 donor, 1 recipient). In this case, the numbers you present kind-of work out. And sure, a risk of HIV (or whatever) infection versus certain death is worth it in any scenario. (Especially now that HIV/AIDS is chronic and treatable rather than terminal).
Many scenarios involve heavy blood loss and require more than what is normally given by a donor in a single donation. This means drawing on the pool of available blood, so multiple donations will be used of the same type, but they won't be from the same donor.
This raises the risk of transfusing infected blood significantly which is one of the reasons that the screening for blood donation harshly excludes anyone who fits in one or more higher risk groups.
I'm a donor and where I live you can't donate blood if you've received blood (inter-species tissue exchange), lived in UK in the 90s (mad cow disease risk), were born in sub-Saharan Africa (HIV risk) and a couple of others. This includes ever having had male/male sex (very high risk group). Ever been paid for sex? Out. Ever exchanged drugs for sex? Out. The list goes on and on.
The 'in the last 12 months' items are again a form of risk management (they include new partners, tattoos, piercings, infections, illness, surgery, travel to risk countries, etc).
All blood gets tested and though false negatives are still possible, most infections are statistically close enough to 100% detectable after 6 months.
Where I live it's also illegal to sell parts of your body (which includes your blood). The idea behind that is that legalizing this would create a predatory market between people with money and those on the bottom rung of the ladder (poor, addicted, high-risk, all of the above). That's not a hard sell, but it also acts as a filter in the blood donation system. People who are most likely to sell blood are the people you don't want giving blood in the first place.
A detail in my country is that the donation forms don't ask about your sexual orientation, which is irrelevant. If you identify as homosexual (male/male or female/female) but have never had male/male sex, you're good to go.
Blood donation is a region where you're just harshly subjected to selection based on statistics which place you in one risk group or another. Discrimination doesn't factor into it.
Wait, doesn't that exactly refute your point? Presumably, gay men and gay women have different health profiles, whereas they have similar "moral" profiles to an up-tight conservative. I think the statement makes more sense like:
> And no, it is not for moral issues because they don't turn away gay women.
[0] http://www.redcrossblood.org/donating-blood/eligibility-requ...
Someone else's life is on the line. They need to be sure.
Though I must admit, I'm surprised the policy is in place with marrow donations. With blood donations, sure, transfusions are a routine thing and your blood is highly replaceable. With marrow donations, though, someone may need your marrow or they'll die. I'd think a match, even if it carried a slight statistical chance of HIV, would be something they'd want to know about.
On the other hand, many people who need a marrow transplant have some flexibility as to when they can get the donation. This is why the guidelines are so strict: the risk/reward ratio is balanced in favor of caution.
If, however, I had sex with a man once in the last 30 years I am not eligible.
Why is it more sensible to turn away gay people then it is to turn away people who have regularly exposed themselves to HIV?
I'm pretty sure if my life was on the line I'd rather get both bone marrow and HIV than neither. HIV is essentially a chronic disease nowadays in the developed world, and if there was any suspicion of HIV in the donor they could add antiretrovirals into the cocktail I'd already be taking.
It's not as if gay men are the only ones to get HIV, anyways.
http://www.onematch.ca/ http://www.blood.ca/CentreApps/Internet/UW_V502_MainEngine.n...
The first site is supposed to be more current, but isn't rendering properly for me on Firefox. On the second site, Scroll to the bottom for the button to start the process.
UK
http://www.nhsbt.nhs.uk/bonemarrow/qa/index.asp#howcan
It appears that you opt-in when you donate blood. I don't see mention of an at-home swab program.
Germany
http://www.stammzellspenderdatei.de/
Others
http://marrowdrives.org/bone_marrow_donor_programs.html
(Scroll down to see the partner organizations in many countries)
http://www.anthonynolan.org/What-you-can-do/save-a-life/Onli...
Takes like five minutes of your life. Could save someone else's.
Or sign up at the Red Cross centre when you're in there to donate blood - they'll take an extra blood sample for testing purposes.
> I fussed around with the website to update my contact data
If someone did a better job designing or testing the UI on that web app, who knows how many extra lives may have been saved.
When I think about it, I've worked on at least three projects where bugs or usability issues could potentially have a direct impact on someone's life. Yet we didn't reflect on it much in the course of our day-to-day routine.
Being a donor is a bold action, but don't underestimate the impact of your development work as well.
We also had an equally important test system so the campus police could test their familiarity with the procedures daily. This is the kind of app that saves lives; hence the line-by-line code reviews of every single change to the application, and backup procedures for backup procedures in case something breaks.
It is true, not every day you get to work on something like that. However, when you do, it always makes the hair on the back of your head stand up each time you find a bug.
http://www.anthonynolan.org/What-you-can-do/save-a-life/Onli...
I wonder if there's a decent solution on the forwarding thing with some kind of unique id as metadata on an address, so if something's important someone in possession of the old address can find you through the ID? Or maybe that's just not practical, as no one would use it/retain the info unneeded in the short term.
After a visit to India earlier in the year, to oversee development of software for my new biz, I was awestruck at the conditions people were living in. Seeing this made me want to do something to help, and therefore decided to contribute a portion of every dollar earned to build water wells in developing countries for clean water.
I will definitely look into this as well to help...
I'm quite surprised that there are no donor centers in other countries. Are there? Most of these(or all) are first world countries - it scares me to think the chances of people in third world countries if even the ones listed here have a hard time looking for donors.
Signed up!
To the extent it's still relevant in the modern world, our postal system really needs to work a little more like the phone system.
I can be pretty much anywhere in the US (or really, the world, if I want to pay international roaming fees), someone can dial my well-known phone number, and my phone will ring.
For ordinary first class mail, I should be able to generate unique ID numbers on the USPS's website, and associate them with any physical US address I wish at any time. Then I can keep one or more postal IDs pointed at the location(s) I actually receive mail at, and the scanners (virtually all mail is routed by optical scanners now, even hand-addressed envelopes) can just read the ID number and stamp on the current physical address.
if you get a new phone number, your old one probably won't forward to you, and once someone else has that new number, you will never get forwarded calls. at least with a mailing address, new people can occupy that same old address but any mail to it will still forward based on your name.
And I don't need a new phone number, that's kind of the point. I can switch providers and still keep my number. I can move to the other side of the country and keep my number. That's what I want out of the post office.
I do find this surprising as for me, forwarding requests have always worked as expected. Could be a management problem in your area.
> Did you know that, when the marrow donation center finds a
> match, they try desperately to reach the potential donor? Even
> if that person has moved from their dorm room long ago, even if
> their contact information has changed, even if they’re in a
> different state, even if 16 years have passed? They try. They
> look all over for ways to reach that person.The phone equivalent would have tried his dorm and that would have been that. He never would have even known that they had tried to contact him.
I can't help but think that there might be a business idea wrapped up in there somewhere, or at the very least, another product for USPS to offer.
some other smaller companies do receiving and forwarding, some will even scan the mail you receive so you can view it online and see whether it's junk mail or not - http://www.virtualpostmail.com/
You'll notice from my hedging that I only half believe the story. Also, it may be a true story, but may have happened in the '50's or something.
How do they submit forwarding updates to remote post offices? Well, they've already got an in-house network with QoS guarantees, so of course they use that. Yes, I'm referring to letter delivery itself - a good lesson in technology sticking around because it "works".
They do have a new service called "premium forwarding" or something where they want to gouge you something like $20/mo for making their life easier too (and to encourage you to use it, they take away the ability to update your normal forwarding online!). It's bureaucracy, perverse incentives abound! I've also heard (from a letter carrier) that the USPS is looking to stop Saturday delivery, so they've been holding back mail on Saturdays to justify it being a light day.