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>I still regularly encounter people who are spitting angry against transgender folks and then later in the conversation will completely unironically talk about how much they love the cyberpunk genre.

There is a difference between messing with your body and augmenting it. Transhumanists generally believe in augmenting the human body with cybernetic parts, not changing the body's internal chemistry.

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Then how do you explain common transhumanist ideas like nootropics and biohacking? I think the line you've drawn is a bit arbitrary.

Indeed, I don't think the issue is with the use of chemicals or not.

But about, as the parent pointed, improvement. Even in a transhumanist society, someone with eyes on its feet or a mechanical arm without any usefulness would be regarded as stupid or mentally ill.

Not all modifications are good &/or transhumanists.

>I think the line you've drawn is a bit arbitrary.

On second thought, what I should have said was "transhumanists focus on improving the human body". Transitioning may improve your mental health (debatably) but it does not improve your physiological capabilities, and in case of MTF transition arguably worsens your body (bone density, muscle mass, fat distribution and so on)

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