I'm not sure it's all that radical. Sure, you can think of ways to completely clean slate redesign various applications and systems. But equally there are reasonably straightforward ways to integrate it into existing systems to achieve good speedups.

Are changes to everyones model of computing actually radical? I mean, I understand that taking advantage of the fact that memory actually persists is actually somewhat non-trivial when done via byte-addressable accesses, and that even with libraries that will be doing these things, developers gain a new set of properties to worry about, but... isn't this all optional? Why can't software treat persistent memory as just a lot denser RAM?