Also I think you're conflating workloads with operations. Sure, the occasional operation like EXISTS and LIST operation might be faster, but surely most workloads do a lot more than checking a trillion things for existence?
I feel like everything you wrote just makes the case against Optane better than even I could. There seems to be little if any clear performance benefit (being generous here, given slowdowns are also possible as you noted!) to most people's workloads to justify upending everyone's current model of computing. Something like this would probably need to deliver at least an order of magnitude of visible speedup in typical use cases for people to consider it. Which isn't to say some niche workloads might not see 2+ orders of magnitude performance improvement, but the rest of the world clearly won't; why should they have to pay the price for niche use cases?