if you think React is big, you'll be sad by the 2 MB mandatory runtime you have to download just to run your Blazor WASM code, which can add megabytes on top.

That said, if your application is actually complex enough to warrant this upfront download cost, might make sense.

YMMV as always

EDIT: in case it wasn't obvious, I was talking about Blazor WASM not Blazor server