Pandemics, disease control, and epidemiology :)
i.e. infected = base. New infection rate, spread, R0 etc = 1st derivative. R0 increasing or decreasing = 2nd derivative.
Environment, Metereology and Climate.
Climate/phenomenon (i.e. global warming) = base. Is it increasing/decreasing = 1st derivative. Is the rate of change increasing or decreasing (i.e. as carbon emissions start to enter the atmosphere after the industrial revolution) = 2nd derivative.
You could get really fancy and say that climate is a statistical function on localised individual weather observations which follow the above pattern. And that you can take a derivative on the numbers generated by these individual observations themselves measuring localised 1st/2nd derivatives. Does that make it a third derivative? Exercise left for the reader :)
Economics, Finance, Risk and Regulation.
Closely related to interest rates and equilibrium funnily enough. Lets take mortgage stock/book cause it's easy.
A percentage of mortages go into default. 1st derivative. Are the rate of defaults (or adverse events) increasing or decreasing: 2nd derivative. (am i right on that, i haven't thought too hard, just whipped it out).
Indeed, I imagine it would come up in a lot of places where things can transition between states of equilibrium. To observe equilbrium and transition to another state, you may need to first measure 1st derivative. 2nd derivative may then inform on whether the system is transitioning to a new equilibrium/state or not. Sorry if that's too abstract.
Engineering
I presume higher derivatives would come up anywhere there's possibly of feedback loops. 2nd derivative can tell you if the system is heading towards catastrophic failure.
Which brings us to...
Anything (or at least a lot) of fields that invovle practical or empirical measurements or estimations of exponential effects. Since in the real world most exponential effects have a natural limit or regulator, we're often interested in knowing when the phenomenon hits its natural limit. And this means observing the rate of change (2nd derivative) on the rate of change (1st derivative) to pinpoint where and when the exponential behaviour is breaking down.