Sure it is.
3d file managers[1] never took off. With todays hardware they'd be a lot nicer to use.
Users have been limited to quite small (sorry about my incorrect terminology here, I'm going to go read some man pages) total virtual screen size within which their windows were located. Now graphics cards, and system memory, are huge; this leads to possible radical new interfaces.
Imagine a "Zoomable UI" - documents open in their own full size window; any document opens in its own window tiled next to it; the user can zoom in as far as they like to do detail work, or out as far as they like to organise all these documents. Programs would open toolbars in their own windows. Any toolbar would be able to work on any document (because it's Unix, so all input and output is text, right?) - but the result wouldn't necessarily make any sense.
That's not particularly radical; tiling WMs exist already.
[1] (http://nooface.net/3dui.shtml) {my favourite is FSV.}