Villages in my country are losing their only stores because the stores don't get enough business to make it worth the cost. These are usually villages with a high average age. What happens to the residents? Many of the elderly don't have a car. They can't exactly go over to the next town and buy a week's worth of groceries if they can't carry these.
The store closing essentially kills off the village over time. Heavy additional costs to doing business can mean that a community just goes without any service at all. It might not be a common issue now, but if it ever does appear then it's not like you can turn the economy back on like you would flip a switch.
Also, there is no ADA compliance inspector. One of their customers would have to sue or report them. If they get reported then the remediation is to come up with a plan to address the concerns in a reasonable time. You really only get in trouble when you start willfully refusing to address issues. Again, businesses have had decades to address these. If they close and kill a town now, it’s because they didn’t do the right thing when times were good for them.