I use ODM to map large areas (100-300) acres regularly. It's pretty much fire and forget on AWS spot instances.

Combined with Dronelink, my workflow is largely automated. Just a few more pieces I'd need to have in place to be able have it be more or less hands off.

The next piece I want to tackle is creating a watched directory or S3 bucket that automatically spins up a spot instance, monitors for the completeness of the work, downloads the results to S3, and shuts down the spot instance. Then all I'd have to do is watch the drone fly and move photos into a folder.