The building he designed in Cleveland, the Peter B. Lewis building on the campus of Case Western, suffers from the winter fate of having ice and snow avalanche off the classic Gehry roof design. Initially, I don't think this was accounted for and people were getting hit. Eventually, they figured out that they needed more specific walkways where the snow wouldn't hit pedestrians.
The building also stood out substantially for quite some time. That part of campus was mainly comprised of buildings from the early 1900's. Today, a lot of new construction has sprung up around that area so it's not quite as jarring, but like any Gehry building, it still stands out.